Why gentamicin levels are taken pharmacokinetics dosing monitoring creatinine clearance

>> YOUR LINK HERE: ___ http://youtube.com/watch?v=p4Fu-ZojQh4

This video goes through the concept of taking gentamicin levels are why they are taken in order to adjust a patient's gentamicin dosing. Also include gentamicin pharmacokinetics, dosing, monitoring, and the Cockroft-Gault formula for creatinine clearance. (Sorry about the choppy audio!) • Time stamps: • 0:00 Introduction • 1:18 Plasma concentration curve • 1:46 First order kinetics • 2:45 Post antibiotic effect (POE) • 2:59 Once daily dosing vs multi-day dosing • 4:16 Concentration dependent killing • 4:58 Why once daily is preferred • 5:45 Gentamicin in renal impairment • 6:51 Initial dose • 7:31 Ideal body weight vs actual body weight in obesity • 8:24 Deciding on the interval - taking gentamicin levels • 10:41 Renal function • 11:38 Creatinine • 12:27 Cockroft-Gault equation for creatinine clearance • • Hospital pharmacists should also refer to their hospital gentamicin dosing guidelines. • Websites used in the video: • IMPACT Body Weight Calculator: https://impact.chp.gov.hk/calculator_... • National Kidney Foundation: https://www.kidney.org/atoz/content/gfr • MDCalc CrCl calculator: https://www.mdcalc.com/creatinine-cle... • IMPACT CrCl calculator: https://impact.chp.gov.hk/calculator_... • I write online tutorials going through Hong Kong registration past papers for pharmacists at www.pharmacyexamquestions.com

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