Pentose Phosphate Pathway Oxidative Phase Mnemonic for MCAT

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Study this Pentose Phosphate Pathway - Oxidative Phase mnemonic and other mnemonics with Pixorize. • The pentose phosphate pathway begins with glucose-6-phosphate, a molecule which itself has several metabolic fates. Glucose-6-phosphate is usually thought of as coming from glycolysis, which helps explains its other name: the hexose monophosphate shunt. This is because the pentose phosphate pathway provides an alternative shunt for hexose monophosphates, like glucose-6-phosphate. • Since glycolysis and the pentose phosphate pathway are directly related, it should help you remember that the pentose phosphate pathway takes place in the cytoplasm. • When examining the pathway in detail, we can break it into two phases: an oxidative phase and a non-oxidative phase. • The oxidative phase is characterized by the oxidation of molecules, starting with of course glucose-6-phosphate. This oxidation is used to reduce NADP+, forming high-energy NADPH molecules. NADPH are distinct and important products of the pentose phosphate pathway, and their formation is a hallmark of the oxidative phase. • The oxidative phase ends with the production of ribulose-5-phosphate, which is the first pentose phosphate produced. In the non-oxidative phase, we’ll touch further on the production of pentose phosphates for which the pathway is named. • The pathway is regulated based on the energy needs of the cell and the body. When NADP levels are high and NADPH levels are low, the pathway is stimulated in an attempt to increase levels of NADPH. Conversely, when NADPH levels are high, the pathway is inhibited. • • Subscribe for more: https://bit.ly/2yybxhm • Study interactive image: https://pixorize.com/view/5692 • #MCAT #premed #pentosephosphatepathway

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