CrossBridge Cycle of Muscle Contraction

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Muscle contraction requires myosin to bind to actin. Calcium moves allows troponin and tropomyosin to reconfigure their shapes so that myosin can bind to actin. As myosin ejects its ADP, the powerstroke occurs. Myosin then binds to a new ATP and hydrolyzes it to ADP. This hydrolysis changes the shape of myosin so that it is now ready and able to bind once again to actin. This process continues as long as calcium and ATP are plentiful. • Find diagrams, notes, and practice questions at http://www.sciencewithsusanna.com

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