Ubiquitylation and destruction of cyclins

>> YOUR LINK HERE: ___ http://youtube.com/watch?v=tql34mTXizs

SCF is responsible for ubiquitylation and destruction of G1 phase cyclins and Apc/c is responsible for ubiquitylation and destruction of S and M phase cyclin...

how to destruct cyclins and regulation of cyclin-CDKs complexes..
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