Animation rhinovirus A16 binds receptor hilghight structure features











>> YOUR LINK HERE: ___ http://youtube.com/watch?v=tzDZUnqhI3M

Rhinovirus A16 - animation to mimic receptor binding. • NOTE: this is only an animation and does not take into account ICAM-1 receptor recruiting. • The virus particle is rotated so that structure of the surface and of the canyon is clearly seen. See ICAM-1 http://en.wikipedia.org/wiki/ICAM-1 • Movie created in 1994 for a molecular graphics contest on a Silicon Graphics (sgi). • This is a reassembly of the saved original frames. • This version was created at 12 frames/sec with the H.264 compression scheme and saved as Mpeg-4. - However, YouTube might have modified some setting after upload. • © 1994 - Jean-Yves Sgro, Ph.D. - Senior Scientist, University of Wisconsin-Madison, WIsconsin-USA • Images/Animations can be used for in-class teaching and educational seminar presentations. • Commercial usage is prohibited without prior authorization. • More images and movies on Virusworld at http://www.virology.wisc.edu/virusworld/ • GRASP rendering of human rhinovirus A16. PDB ID: 1AYM. DOI:10.2210/pdb1aym/pdb • COLORS: Radial depth-cueing • REFERENCES: • PDB STRUCTURE: Primary citation: • The refined structure of human rhinovirus 16 at 2.15 A resolution: implications for the viral life cycle. Hadfield, A.T., Lee, W., Zhao, R., Oliveira, M.A., Minor, I., Rueckert, R.R., Rossmann, M.G. • Journal: (1997) Structure 5: 427-441 • PubMed: http://www.ncbi.nlm.nih.gov/pubmed/90... • GRASP SOFTWARE: Nicholls A, Sharp KA, Honig B • Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons. Proteins 1991;11(4):281-296 • http://wiki.c2b2.columbia.edu/honigla... • Images created for the video contest of the 1994 annual meeting: • rhinovirus meets receptor • Rhinovirus 16, represented as a radially depth-cued molecular surface, turns, rolls and eventually meets a model receptor on a model cell. • REFERENCE: 1994 Molecular Graphics Art Show and Video Show • David S. Goodsell, Teresa A. Larsen, and T.J. O'Donnell • J. Mol. Graphics 13:223-234 • http://www.ncbi.nlm.nih.gov/pubmed/85... • There is NO AUDIO to this movie.

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