Thrombus in Transit across a Patent Foramen Ovale NEJM











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Hypoxemia and shock developed suddenly in a 67-year-old woman with atrial fibrillation who had been admitted to the hospital for management of an acute ischemic stroke. A computed tomographic pulmonary angiogram showed pulmonary emboli in the main pulmonary arteries, right ventricular dilatation, and a large thrombus in transit through a previously unknown patent foramen ovale (PFO); a subsequent transthoracic echocardiogram showed a thrombus crossing through the PFO into the left atrium. • Read the full clinical case: https://nej.md/3MIDNET

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