Youtor
Spironolactone Mechanism side effects precautions
>> YOUR LINK HERE: ___ http://youtube.com/watch?v=ukKIkMEswvs
Spironolactone is a spiro compound with C21 pregnane nucleus and five membered lactone ring. It acts as potassium sparing diuretic therefore promotes sodium excretion at the same retaining potassium in the body. • It is metabolised to one of the active metabolite canrenone and both the parent drug and this metabolite act as competitive antagonists at aldosterone receptors. • #Aldactone • #AldosteroneAntagonist • #PotassiumSparing • 0:00 Introduction • 2:13 How does Spironolactone act? • 4:28 Metabolism of spironolactone • 5:14 How it is given? • 7:26 Other side effects • 7:46 Drug interactions • 9:13 Other interactions • 9:39 Precautions • 10:52 Where is it used?
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