Atorvastatin Nursing Considerations Side Effects and Mechanism of Action Pharmacology for Nurses

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Grab our free cheatsheet covering the 50 most commonly prescribed medications right here: http://www.NURSING.com/50meds • View the blog post here: https://www.NURSING.com/atorvastatin-... • Listen to all the episodes at: https://www.NURSING.com/medmaster-pod... • Atorvastatin • Generic Name: atorvastatin • Trade Name: Lipitor • Indication: management of high cholesterol (hypercholesterolemia), primary prevention of cardiovascular disease • Action: lowers total cholesterol as well as LDL while slightly increasing HDL. Inhibits HMG-CoA reductase which plays a role in the liver in cholesterol formation • Therapeutic Class: lipid-lowering agent Pharmacologic Class HMG-CoA reductase inhibitor Similar Medications simvistatin (Zocor), rosuvastatin (Crestor) • Nursing Considerations: •  contraindicated in active liver disease •  may cause rhabdomyolysis •  monitor renal function •  monitor serum cholesterol before, about 4 weeks after starting, and frequently during drug therapy •  monitor liver function tests •  instruct patient to report muscle weakness (sign of rhabdomyolysis)

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