Whats Wrong with Strattera

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Main Chapters: • 00:00 Intro - What's Wrong with Strattera? • 00:10 Take home message • 00:59 History of Strattera • 03:33 Strattera compared to Alternatives • 10:51 Effects of Strattera for ADHD • 12:06 Side effects of Strattera • 17:34 Study comparing Strattera and Qelbree • 21:24 Conclusion • 22:27 Questions • ----- • Follow / dockruse on Medium for hundreds of full length articles on this subject and more! • Access to full Medium articles requires paid membership. • ----- • The FDA approved Strattera (atomoxetine) two decades ago as the first non-stimulant for the treatment of ADHD. Although designed with the hope of being an effective antidepressant, it had more clearcut results for ADHD. But from the beginning, many, many people haven’t responded well to the medication. It seems to take a long time to work, and lots of people have troubling side effects. And that’s not just in comparison to stimulants. A recent head to head comparison with another non-stimulant for ADHD, Qelbree (viloxazine) found that Strattera was less effective, had more side effects, and took longer to provide benefits. • If Strattera is working for you, great, keep taking it. But if your response is mediocre or worse, there are several other non-stimulants that might help you more, including Qelbree, Wellbutrin, guanfacine, and even Cymbalta (duloxetine). • References: • Extended-Release Viloxazine Compared with Atomoxetine for Attention Deficit Hyperactivity Disorder (2023) • https://link.springer.com/article/10.... • Atomoxetine in patients with ADHD: A clinical and pharmacological review of the onset, trajectory, duration of response and implications for patients • https://journals.sagepub.com/doi/10.1... • The Effect of Methylphenidate and Atomoxetine on Heart Rate and Systolic Blood Pressure in Young People and Adults with Attention-Deficit Hyperactivity Disorder (ADHD): Systematic Review, Meta-Analysis, and Meta-Regression • https://www.mdpi.com/1660-4601/15/8/1789 • Full Chapter list: • 00:00 Intro - What's Wrong with Strattera? • 00:10 Take home message • 00:59 History of Strattera • 03:33 Strattera compared to Alternatives • 04:31 Strattera Receptor Binding Data • 06:02 Cymbalta / Qelbree / Wellbutrin • 07:46 Ritalin / Reboxetine / Paxil • 09:03 Strattera in Live Animals and Humans • 10:51 Effects of Strattera for ADHD • 12:06 Side effects of Strattera • 14:06 Suicidality / Blood Pressure / Heart Rate • 16:00 Drug Interactions / Dosage • 17:34 Study comparing Strattera and Qelbree • 19:50 Study Analysis • 21:24 Conclusion • 22:27 Questions • 22:43 Side effects of Adderall and Alteranatives • 23:38 Is Cymbalta working on Dopamine? • 24:27 Modafinil for ADHD • 26:58 Medication Risks of Panic attacks and Addiction • 28:57 Guanfacine for ADHD • 29:43 Amphetamine vs Methylphenidate • 30:41 Outro • Streamed live October 4, 2023 • ------------------------- • Psychiatrist, neuroscientist, and author John Kruse, MD, PhD presents practical, actionable, well-researched information about treatment options that scientists and clinicians recommend for adult ADHD and other mental health conditions. Subscribe if you're curious about how neuro-atypical brains can optimize their functioning in our shared, and somewhat strange, world. • Dr. Kruse has posted talks in both the live and the video sections of this channel. Thumbnails on ADHD topics have a pink background, and those on more general mental health topics have a purple background. A small collection of ADHD-Trump videos have an orange background. • You're welcome to email him with topics you want discussed or people you think he should interview. • [email protected]

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