SGLT2 inhibitors Canagliflozin Dapagliflozin Empagliflozin Mechanism of action











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SGLT2 inhibitors • Thanks for watching • Drugs- Canagliflozin Dapagliflozin Empagliflozin • HOW DO SGLT2 INHIBITORS WORK? • SGLT2 inhibitors work by preventing the kidneys from reabsorbing glucose back into the blood. • This allows the kidneys to lower blood glucose levels and the excess glucose in the blood is removed from the body via urine. • The kidneys work by filtering glucose out of the blood and then reabsorbing glucose back into the blood. The proteins that reabsorb glucose are called sodium-glucose transport proteins. • SGLT2 inhibitors block these proteins which means less glucose gets reabsorbed back into the blood and gets passed out of the body via the urine • #SGLT2inhibitors #SGLT2 #Pharmacology

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