Synthesis of Demerol

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Synthesis of demerol involving Grignard reaction, esterification, and alkylation. Practical synthesis involving alkylation of a nitrile instead of an ester. Disconnections and functional group interconversions in the synthesis of demerol. • 00:00 Synthetic Schemes • 00:47 The Grignard Reaction: Synthesis of Phenylacetic Acid • 03:36 Esterification and Alkylation; Summarizing the Synthesis • 05:28 Industrial Synthesis of Demerol • 08:41 Comparing the Syntheses

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