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E2 reactions on alcohols
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Video Source: www.youtube.com/watch?v=DJPwOR8gE-o
directory of Chem Help ASAP videos: https://www.chemhelpasap.com/youtube/ • Alcohols cannot directly undergo an E2 reaction because the OH group is such a poor leaving group. There are two potential solutions. (1) Make the OH into a better leaving group with acid... If the alcohol is protonated with an acid, that proton will simply be removed once the base of the E2 reaction is added. Protonation is not a viable solution. (2) Convert the OH into a different leaving group... Alcohols can be converted into other leaving groups, such as halides or a tosylate. These leaving groups will react as expected with base to form the E2 alkene product. Therefore, alcohols can undergo an E2 reaction if the alcohol is first converted to a halide or tosylate.
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