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Brown vs White Adipose Tissue Roles of Pericardial Fat
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Video Source: www.youtube.com/watch?v=IxBLCklaw7k
Description at: https://johnsonfrancis.org/profession... Pericardial fat can behave as both brown and white adipose tissue in different situations. • In healthy persons, epicardial fat behaves like brown adipose tissue and utilizes fatty acids, preventing local proinflammatory action and providing nutrition to adjacent tissue. On the other hand, in obesity it functions like white adipose tissue which causes lipolysis and release of fatty acids which are proinflammatory. In mouse models, it has been shown that thoracic perivascular adipose tissue is resistant to diet induced macrophage infiltration and may protect the vascular bed from inflammatory stress.
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