Polyol Pathway or Sorbitol Pathway

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Polyol pathway is the metabolism of excess glucose into sorbitol. Sorbitol is a monosaccharide having all six carbon alcohol group (polyol). Sorbitol pathway (polyol pathway) partly explains the microvascular complications seen in uncontrolled diabetes mellitus patients. Osmotic activity of sorbitol is partly responsible for the metabolic changes seen in tissue cells leading to diabetic nephropathy, diabetic retinopathy, diabetic neuropathy, premature cataract. • For REGULAR UPDATES you can consider SUBSCRIBING to this channel: https://goo.gl/eMs6rw • For short write up of theory on USMLE Biochemistry and other topics on food and nutrition, obesity, weight loss tips you may visit my site: • http://www.drmungli.com/ • You can follow my Facebook page Biochemistry Made Easy: https://goo.gl/23S9Y7 • checkout other awesome channels to learn biochemistry and other subjects from: • ThePenguineProf: https://goo.gl/ySNURB • Osmosis: https://goo.gl/d1zBs1 • Armando: https://goo.gl/jcYwwR • Khan Academy: https://goo.gl/7YmIf9 • Nucleus Medical Media: https://goo.gl/xdlqsr • Trending medical youtube channels: https://goo.gl/nUuJOL • 20 useful sites for medical students: https://goo.gl/aPnc19 • Biochemistry single line questions site: https://goo.gl/PFCewk

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