Class 17 Chemical Evaluation of Drug Quality Control of Drugs of Natural Origin Part 03

############################# Video Source: www.youtube.com/watch?v=TZMz8_fzlPI

Download Solution Pharmacy Mobile App to Get All Uploaded Notes, Model Question Papers, Answer Papers, Online Test and other GPAT Materials - https://play.google.com/store/apps/de... • 1. Playlist Pharmacognosy lecture Videos Unit 1 • • Class (08) = Natural Sources of Drug ... • 2. Quality control of Drug Part 2 https://studio.youtube.com/video/yHUx... • 3. Quality control of Drug Part 1 https://studio.youtube.com/video/F4cN... • 4. Qualitative test for Alkaloid • • Phytochemical Test for Alkaloid | Qua... • 5. Foam test for Saponin • • Saponin Foam Test | Saponin Identific... • 6. Qualitative test fro Tannin • • Phytochemical Test for Tannins (Engli... • 7. Qualitative test for Flavonoid • • Phytochemical Test for Flavonoid | F... • Evaluation of drug means confirmation of its identity and determination of its quality and Purity of drug • Methods of drug Evaluation • 1. Organoleptic/Morphological method 2. Microscopic method 3. Physical evaluation • 4. Chemical evaluation 5. Biological evaluation • 4. Chemical evaluation. A number of chemical methods are used to evaluate of main constant of drugs and include: • 1. Qualitative chemical tests • 2. Quantitative chemical method • 3. Chemical Assay • 4. Instrumental Analysis • 1) Qualitative chemical tests: Determination of active constituents in a drug by chemical process is referred to as chemical evaluation. • (a) Test for alkaloids: i. Mayer test: ii. Hagar Test iii. Dragendorff’s test iv. Wagner • (b) Test for glycosides: • (i) Tests for saponin glycosides: a. Foam test: b. Haemolytic test: • (ii) Test for anthraquinone glycoside: Borntranger’s Test: • (iii) Chemical tests for cardiac glycosides: a. Raymond’s test: b. Legal test: c. Killer killiani test: d. Baljet test: e. Kedde test: • (c) Tests for tannins: i. Gelatin test: ii. Goldbeater’s skin test: • (d) Test for carbohydrate: i. Molish test: ii. Fehling Test: iii. Benedict test: iv. Iodine test: • (e) Test for Phytosterol: i. Salkowski test: ii. Liebermann Burchard test: • (f) Test for proteins: i. Biuret test: • 2. Quantitative chemical methods of Evaluation: • Quantitative physiochemical constants like acid value, iodine value, acetyl value, hydroxyl value and Saponification value, etc. are employed for fixed oil and fats. • (i) Acid value: The acid value is the number of mg of potassium hydroxide required to neutralize the free acid in 1 g of the substance. Example: (i) Yellow bees wax: 5- 8 (ii) Castor oil: not more than 2 • (ii) Saponification value: The Saponification value is the number of mg of potassium hydroxide required to neutralize the fatty acid, resulting from the complete hydrolysis of 1 g of the oil or fat. Example: Linseed oil: 188-196 • (iii) Iodine value: The iodine value is the number, which expresses in grams the quantity of Iodine, which is absorbed by 100 g of the substance. Example: Olive oil: 79- 88 • 3. Chemical Assay • Approximate value of total phytoconstituent in a crude drug. Example Total alkaloid in belladonna leaf, Total vitamin in cod liver oil, Strychnine in Nuxvomica • 4. Instrumental Analysis • Analysis of chemical group of phytoconstituent in by Chromatographic (TLC, HPTLC, HPLC, GC) and Spectroscopic method (IR, NMR, MS, UV-Visible spectroscopy). • Get in touch with the solution by just clicking following links- • Facebook Group- / solutionpharamcy • Facebook Page- / pharmavideo • New channel (Pharmacy Dictionary) - / @pharmacydictionary • Instagram- / solutionpharmacy • E-Mail for official and other work - [email protected] • LinkedIn- / pushpendrakpatel • #solutionpharmacy #Pharmacologyclass #GPATonlinetest

#############################

New on site