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#DNA #DNAreplication #Deoxyribonucleicacacid #Nucleotides • #Thymine #Adenine #Cytosine #Guanine #CellBiology #apbiology • DNA Replication | RNA | Nucleotide | Cell Biology | Genetics🧬 • Like this video? • Sign up now on our website at https://www.DrNajeebLectures.com to access 800+ Exclusive videos on Basic Medical Sciences Clinical Medicine. These are premium videos (NOT FROM YOUTUBE). All these videos come with English subtitles download options. Sign up now! Get Lifetime Access for a one-time payment of $45 ONLY! • Sign up now on our website at https://members.drnajeeblectures.com/ • --------------------------------------------------------------------------------------------------------------------------- • Why sign up for premium membership? Here's why! • Membership Features for premium website members. • 1. More than 800+ Medical Lectures. • 2. Basic Medical Sciences Clinical Medicine. • 3. Mobile-friendly interface with android and iOS apps. • 4. English subtitles and new videos every week. • 5. Download option for offline video playback. • 6. Fanatic customer support and that's 24/7. • 7. Fast video playback option to learn faster. • 8. Trusted by over 2M+ students in 190 countries. • --------------------------------------------------------------------------------------------------------------------------- • ▬▬▬▬▬▬▬▬▬▬ Contents of this video ▬▬▬▬▬▬▬▬▬▬ • In molecular biology, DNA replication is the biological process of producing two identical replicas of DNA from one original DNA molecule. DNA replication occurs in all living organisms acting as the most essential part for biological inheritance. • In molecular biology, DNA replication is the biological process of producing two identical replicas of DNA from one original DNA molecule. DNA replication occurs in all living organisms acting as the most essential part for biological inheritance. This is essential for cell division during the growth and repair of damaged tissues, while it also ensures that each of the new cells receives its own copy of the DNA. The cell possesses the distinctive property of division, which makes replication of DNA essential. • DNA is made up of a double helix of two complementary strands. The double helix describes the appearance of a double-stranded DNA which is thus composed of two linear strands that run opposite to each other and twist together to form. During replication, these strands are separated. Each strand of the original DNA molecule then serves as a template for the production of its counterpart, a process referred to as semiconservative replication. As a result of semi-conservative replication, the new helix will be composed of an original DNA strand as well as a newly synthesized strand. Cellular proofreading and error-checking mechanisms ensure near-perfect fidelity for DNA replication. • In a cell, DNA replication begins at specific locations, or origins of replication, in the genome which contains the genetic material of an organism. The unwinding of DNA at the origin and synthesis of new strands, accommodated by an enzyme known as helicase, results in replication forks growing bi-directionally from the origin. A number of proteins are associated with the replication fork to help in the initiation and continuation of DNA synthesis. Most prominently, DNA polymerase synthesizes the new strands by adding nucleotides that complement each (template) strand. DNA replication occurs during the S-stage of interphase. • DNA replication (DNA amplification) can also be performed in vitro (artificially, outside a cell). DNA polymerases isolated from cells and artificial DNA primers can be used to start DNA synthesis at known sequences in a template DNA molecule. Polymerase chain reaction (PCR), ligase chain reaction (LCR), and transcription-mediated amplification (TMA) are examples. In March 2021, researchers reported evidence suggesting that a preliminary form of transfer RNA, a necessary component of translation, the biological synthesis of new proteins in accordance with the genetic code, could have been a replicator molecule itself in the very early development of life, or abiogenesis. • --------------------------------------------------------------------------------------------------------------------------- • Join this channel to get access to the perks: • Sign up now on our website at https://members.drnajeeblectures.com/ • Follow us on Facebook:-   / drnajeeb   • Follow us on Instagram:-   / drnajeeblectures  

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