Mesothelioma vs Pleural Metastasis Radiology Lung Cancer or Metastasis to Lung

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Mesothelioma vs Pleural Metastasis Radiology • ➡️ https://MesotheliomaUSA.net • • • According to our results, the three most common findings of pleural malignancies were pleural thickening, free pleural effusion and parenchymal infiltration. Similarly, in an article by Moore et al., nodular pleural thickening and pleural thickening 1 cm are named as most helpful CT findings suggesting malignant pleural disease. We noticed that tumor invasion to the chest wall, liver and peritoneum are rarely seen among all cases, but they were more common in malignant mesothelioma compared to metastatic carcinoma. In the study performed by Wang et al., it has been mentioned that MPM is locally aggressive with frequent invasion to the chest wall, mediastinum and diaphragm. • In our study, among malignant mesothelioma cases, pleural thickening, loculated pleural effusion and thickening of the inter lobar fissure were the most prevalent CT findings and the least common ones were hepatic/chest wall invasion, massive pleural effusion, and pericardial effusion. In metastatic pleural disease cases, free pleural effusion, parenchymal infiltration, and pleural thickening were the most common CT findings and invasion to other organs, pericardial effusion, and thickening had the lowest rate in this disease. • Senyigit et al. in their study in 2000 on 117 mesothelioma patients reported that pleural effusion (89%), pleural thickening (82%), mediastinal pleural involvement (66%), and thickening of the interlobar fissure (53%) are the most common CT findings in mesothelioma patients. In a study conducted by Ng and colleagues on 70 MPM patients, pleural thickening (94%) and pleural effusion (76%) were the most common pretreatment findings similar to a study carried out by Sahin et al on 84 MPM patients. Wang et al. named unilateral pleural effusion, nodular pleural thickening, and thickening of interlobar fissure the key CT finding of MPM. Also, in a study on 92 mesothelioma cases in 2009 by Seely and colleagues, pleural thickening was detected in all patients. They reported 87% pleural effusion in mesothelioma patients, which is different to our result, but they also confirmed that massive pleural effusion is not common in mesothelioma. Kawashima and Lidshitz also mentioned pleural thickening (92%) as the most common finding in MPM. Philippe Grenier wrote in his article that malignant pleural effusion is the most common manifestation of metastatic involvement, similar to our result. • Comparing the two groups, pleural thickening (P = 0.05) and thickening of the interlobar fissure (P = 0.02) are more prevalent in malignant mesothelioma; therefore, they can be considered as important parameters in favor of malignant mesothelioma. • Free pleural effusion is significantly more prevalent in metastatic pleural disease (P = 0.01) while its prevalence is modest in malignant mesothelioma. Massive pleural effusion (P = 0.003) and parenchymal infiltration (P = 0.03) are significantly more common in metastatic pleural disease as well. Therefore, they should be considered as important findings to differentiate these two diseases and parameters leading to the diagnosis of metastatic carcinoma of the pleura. • A study by Yilmaz et al. in 2005 demonstrated findings of malignant mesothelioma as involvement of interlobar fissure (sensitivity of 30%, specificity of 92%) and pleural thickening greater than 1 cm (sensitivity of 60%, specificity of 77%), whereas those of metastatic pleural disease are mediastinal/hilar lymph node enlargement and lung parenchymal involvement. • In Metintas and colleagues’ study which reviewed 99 MPM and 39 malignant pleural disease in 2002, ring-like pleural involvement, mediastinal pleural involvement, and pleural thickness more than 1 cm were considered as independent CT findings for differentiating between MPM and malignant pleural disease with the sensitivity/specificity values of 70/85 and 59/82,respectively. • Generally, this data analysis manifests that CT scan is highly accurate in differentiating malignant pleural mesothelioma and metastatic pleural diseases. Comparing malignant mesothelioma and metastatic carcinoma of the pleura, pleural thickening and thickening of the interlobar fissure lead us to the diagnosis of malignant mesothelioma and massive free pleural effusion insists on metastatic carcinoma diagnosis. • Mesothelioma vs Pleural Metastasis Radiology - Lung Cancer or Metastasis to Lung? • • Mesothelioma vs Pleural Metastasis Ra... • / @mesothelioma1 • #xraycomputed #neoplasm #metastasis • 🔗 https://www.ncbi.nlm.nih.gov/pmc/arti...

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