How Does Ibuprofen Work

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How does Ibuprofen relieve pain? Is it safe to use? What are the risks? These are the questions that I will be answering today! • Do you struggle with depression? Download my FREE resource Top Tips for Dealing with Depression https://bit.ly/3AyLkx4 • Ibuprofen is a Non-Steroidal Anti-Inflammatory Drug (NSAID). It acts to inhibit the Cyclooxygenase (COX) enzyme to inhibit the production of prostaglandins which normally promote pain and inflammation. When COX is inhibited, prostaglandins levels are reduced and pain and inflammation is suppressed. • This is a similar mechanism of action to Paracetamol. The difference is that Ibuprofen also has anti-inflammatory properties, making it a more appropriate drug for the treatment of muscle pain and arthritis. • Ibuprofen also reduces your risk of suffering from deadly blood clots, so it is a pretty good drug...but there are some side effects! • Ibuprofen is known to cause headaches, constipation, diarrhoea, itchiness and stomach pain. The COX enzyme has many roles throughout the body, and by inhibiting it broadly with NSAID drugs like Ibuprofen, there are many different side effects. • An important risk with Ibuprofen is that it can cross the placental lining, meaning if you are pregnant, you should not use Ibuprofen or Aspirin because they can impact on your unborn child. • So in summary, Ibuprofen prevents prostaglandin production by inhibiting COX. As a result, fever, pain and inflammation are reduced, blood clotting risk is lowered, but you are at risk of damaging your gut lining and injuring any fetus that may be present. • If in doubt regarding Ibuprofen, please see your doctor! • BE MY FRIEND: • 💌 Sign up to my weekly email newsletter - https://bit.ly/2YChavA • 📸 Slide into my DMs on Instagram - / travellingscience • 🐦 Teach me how to Twitter - / jctravelscience • 🎬 Check out my YouTube Channel- / thetravellingscientist • 📘 Join the Facebook Community - / travellingscientist • 🍻 Support my channel via Patreon - / thetravellingscientist • 🕺🏼 Learn Laugh at my TikTok - / thetravelingscientist • WHO AM I: • I'm Jesse, a science communicator currently living in Melbourne, Australia. I make videos about the science of health and wellbeing. I also write a weekly email newsletter that contains plenty of interesting information to help you live smarter, happier and healthier. https://bit.ly/2YChavA • GET IN TOUCH: • If you want to reach out, I’d love to hear from you. Feel free to email me at [email protected]. I will try my best to respond but unfortunately I am very busy with work and research...sorry 😭

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