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Cellular barriers to actin nucleation
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Video Source: www.youtube.com/watch?v=v_2_Ydp9G8g
Despite the high concentration of actin monomers in cells, they do not readily form new filaments in the absence of actin nucleators. This is due to the presence of several barriers to actin nucleation, including Profiling, Thymosin beta 4, and Capping Protein (among others). • The animation was produced using Blender, and is available for download at the Goode lab website: http://www.bio.brandeis.edu/goodelab/
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