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From the Pediatric Trials Network The ampicillin in infants study
>> YOUR LINK HERE: ___ http://youtube.com/watch?v=9Gj04FGE5T0
Ampicillin is the most commonly prescribed medication in the intensive care nursery, with an exposure rate of 693 per 1000 discharges, for treatment of bacterial infections including sepsis and meningitis. However, data on dosing and safety in the infant population are incomplete. • • We will examine prospectively collected data from infants admitted between 1997 and 2010 at 305 intensive care nurseries managed by the Pediatrix Medical Group in the United States. A pharmacokinetic data analysis will be performed in combination with retrospective chart review of collected information to verify clinical data. We will examine all recorded laboratory values and diagnoses associated with ampicillin use in infants with and without culture-proven infections. We will compare the odds of adverse events in infants receiving ampicillin alone or in combination with other antibiotics (e.g., cefotaxime, vancomycin, gentamicin). • • https://pediatrictrials.org/
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