MECHANISM OF HORMONE ACTION

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For more information: • http://www.7activestudio.com • [email protected] • http://www.7activemedical.com/ • [email protected] • http://www.sciencetuts.com/ • [email protected] • Contact: +91- 9700061777, • 040-64501777 / 65864777 • • 7 Active Technology Solutions Pvt.Ltd. is an educational 3D digital content provider for K-12. We also customise the content as per your requirement for companies platform providers colleges etc . 7 Active driving force The Joy of Happy Learning -- is what makes difference from other digital content providers. We consider Student needs, Lecturer needs and College needs in designing the 3D 2D Animated Video Lectures. We are carrying a huge 3D Digital Library ready to use. • • MECHANISM OF HORMONE ACTION : Hormones produce their effects on target tissues by binding to specific proteins called hormone receptors located in the target tissues only. Hormone receptors present on the cell membrane of the target cells are called membrane bound receptors and the receptors present inside the target cell are called inter-cellular receptors, mostly nuclear receptors. Binding of a hormone to its receptors leads to the formation of a hormone receptor complex. Each receptor is specific to one hormone only and hence receptors are specific. Hormone – Receptor complex formation leads to certain biochemical changes in the target tissue. Target tissue metabolism and hence physiological functions are regulated by hormones can be divided into groups.Peptide, polypeptide, protein hormones insulin, glucagon, pituitary hormones, hypothalamic hormones etc Steroids cortisol, testosterone, estradiol and progesterone Iodothyronines – thyroid hormones.Amino acid derivative – epinephrine.Hormones which interact with membrane bound receptors normally do not enter the target cell, but generate second messengers. eg. Cyclic AMP, Ip3, Ca++ etc which in turn regulate cellular metabolism.Hormones which interact with intra cellular receptors (steroid hormones, iodothyronines etc). mostly regulate gene expression or chromosome function by the interaction of hormone – receptor complex with genome. Cumulative biochemical actions result in physiological and development effects.

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