Why polycythemia occurs in high altitude











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In this video, the reason why polycythemia happens at high altitudes is discussed. High altitude is a type of hypoxic hypoxia. • At high altitudes there is renal hypoxia which leads to production of hypoxia inducible factor-1 which binds to hypoxia response element in the erythropoietin gene. Finally there is an increase in erythropoietin which leads to the stimulation of pro erythroblast causing an increase in RBC count. • #polycythemia • #highaltitude • #mbbsphysiology • #explainwhyseries • Channel details: • Welcome to my physiology learning channel. I am Dr. Ramkumar S MBBS, MD, DNB physiology. Explain why series will help you to understand concepts in physiology, solve MCQs, answer in Viva, and theory exams. Happy Learning. • Suggested book links • For MBBS students • Ganong’s Review of Medical Physiology - https://amzn.to/3GoArCq • Guyton and Hall Textbook of Medical Physiology - https://amzn.to/3LTgwNp • For Postgraduates in Physiology • Berne and Levy Physiology - https://amzn.to/38QDMhi • Boron Physiology - https://amzn.to/38owktL • Gadgets to make video • Iphone - https://amzn.to/3GsL07Q • Screen recording - https://amzn.to/39ZTE1t • Writing - https://amzn.to/3wQOg9A • Lighting - https://amzn.to/3lMUqRM • Softbox - https://amzn.to/39WW3d5 • Mic - https://amzn.to/3wS8kIR • Tripod - https://amzn.to/3wNHj9n • Mobile holder - https://amzn.to/38QQaxX

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