SRRF Microscopy

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This video shows an example of live-cell Super-Resolution Radial Fluctuation Microscopy (SRRF microscopy), which dramatically improves the resolution and contrast of the resulting images. • In this video, a cell expressing a cytoskeletal marker (lifeact-RFP) and a mitochondrial marker (mito-GFP) undergoes macropinocytosis - the engulfment of large volumes of extracellular liquid. This video highlights the ability of SRRF microscopy to visualize minute structures such as actin fibrils in live cells, at high resolution. • The images in this video have a resolution of ~120 nm; more than double the resolution of an equivalent image series captured by confocal microscopy.","styleRuns":[{"startIndex":0,"length":673,"styleRunExtensions":{"styleRunColorMapExtension":{"colorMap":[{"key":"USER_INTERFACE_THEME_DARK","value":4294967295},{"key":"USER_INTERFACE_THEME_LIGHT","value":4279440147}]}},"fontFamilyName":"Roboto"}]},"headerRuns":[{"startIndex":0,"length":673,"headerMapping":"ATTRIBUTED_STRING_HEADER_MAPPING_UNSPECIFIED"}]}},{"itemSectionRenderer":{"contents":[{"messageRenderer":{"text":{"runs":[{"text":"Reacties staan uit. 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