TCT 23 PICSOAMII Pressure Controlled Intermittent Coronary Sinus Occlusion in AMI

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We are joined by Dr Giovanni Luigi Di Maria (John Radcliffe Hospital, UK) to discuss the findings of the PICSO-AMI-I study (NCT04958421), sponsored by Miracor Medical. • The PICSO-AMI-I study aimed to assess the safety and feasibility of pressure-controlled intermittent coronary sinus occlusion (PiCSO) in patients with ST-elevation myocardial infarction (MI), presenting with TIMI 0 or 1 undergoing percutaneous coronary intervention (PCI) as compared to standard PCI. 25 participants were enrolled in the study, and were randomized 2:1 to either PiCSO or control. • Results showed that in this patient group, PiCSO assisted pPCI was feasible, though it was associated with a prolonged procedural time and increased contrast dye volume and radiation exposure. PiCSO was not associated with an increased rate of adverse events (device and non-device related) at 6 months follow-up. • Interview Questions: • -What are the unmet needs of acute myocardial infarction patients? • -What is the PiCSO Impulse System, and what are its unique features? • -What was the study design and patient population • -What were the late-breaking findings? • -What further study is needed? • Recorded remotely from Oxford, 2023. • Visit Radcliffe Cardiology: https://www.radcliffecardiology.com/?... • This content is intended for healthcare professionals only. • Radcliffe brings medical knowledge, insight and innovation to life for CV clinicians around the world, using our communications creative expertise, our platforms and connections across the community to help transform theory into practice faster. • Like us on Facebook: / radcliffecardiology • Follow us on X: https://x.com/radcliffeCARDIO

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