GraftversusHost Disease Gastrointestinal Tract and Liver

>> YOUR LINK HERE: ___ http://youtube.com/watch?v=v5UaFEfEKTQ

Summary: • Graft-versus-host disease (GVHD) is a condition that can occur after a stem cell using donor cells (an allogenic transplant). This presentation describes how GVHD can affect the mouth, esophagus, stomach, small intestine, large intestine and liver. (In this presentation, the term bone marrow transplant includes bone marrow, stem cell and cord blood transplants.) • Presenter: Theo Heller MB. Bch, FAASLD, National Institute of Diabetes and Digestive and Kidney Diseases • To read the transcript, go to: • https://www.bmtinfonet.org/video/graf... • April 2023, Part of the Virtual Celebrating a Second Chance at Life Survivorship Symposium • The presentation is 38 minutes followed by 21 minutes of Q A. • Key Points: • (12:04): The first 100 days after transplant are typically when acute GVHD may attack the liver, gut and skin, but it can also occur after the first 100 days. • (11:09): The microbiome has become an incredibly hot topic. The best thing you can do for your microbiome is to eat your greens. • (12:59): Symptoms of acute GVHD in the gut include nausea, vomiting, diarrhea, bleeding mucous, feeling full or feeling hungry. • (13:29): Symptoms of GVHD in the liver include nausea, vomiting, not feeling hungry, jaundice and light-colored stool. • (13:47): It’s important to rule out other possible causes of the symptoms of GI and liver GVHD before beginning treatment. • (17:14): Endoscopy is sometimes needed to determine whether symptoms are actually GVHD or another problem. • (22:56): Steroids, such as methylprednisolone, prednisone, and budesonide, are the initial treatment for GI and liver GVHD, and are effective for most people. • (25:24): Chronic GVHD typically occurs after 100 days, is more fibrotic and can affect many more organs than acute GVHD. • (29:14): Liver biopsies are sometimes needed to properly diagnose liver problems. • (34:07): Currently, clinical trials are taking place to explore the effectiveness of fecal transplants and plant-based diets in promoting gut bacteria diversity. • Meet the speaker: • https://www.niddk.nih.gov/about-niddk... • WHO WE ARE: BMT InfoNet is dedicated to providing patients and their loved ones with emotional support and high quality, easy-to-understand information about blood stem cell transplants (bone marrow, peripheral blood and cord blood) and other cellular therapies. Whether you are just beginning your transplant or cellular therapy journey, or learning to manage the joys and challenges of survivorship, • BMT InfoNet is here to help before, during and after treatment. Our goal is to empower you with credible information and emotional support, so that you can take a more active role in decisions affecting your health. http://www.bmtinfonet.org • VISIT US ON SOCIAL MEDIA: • • / bmtinfonet • / bonemarrowstemcelltransplantclub • / bmtinfonet • • / bmtinfonet • / bmt-infonet

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