The Future of Bipolar Disorder Treatment With Psychedelics and Neuromodulation











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Drs Trisha Suppes and Scott T. Aaronson discuss rapid-acting therapies for bipolar disorder and the future of psychedelics and neuromodulation in its treatment. • • Relevant disclosures can be found with the episode show notes on Medscape https://www.medscape.com/viewarticle/.... The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals. • • Resources • • Bipolar Disorder https://emedicine.medscape.com/articl... • • The Effects of Vagus Nerve Stimulation on the Course and Outcomes of Patients With Bipolar Disorder in a Treatment-Resistant Depressive Episode: A 5-Year Prospective Registry https://pubmed.ncbi.nlm.nih.gov/32358... • • A 5-Year Observational Study of Patients With Treatment-Resistant Depression Treated With Vagus Nerve Stimulation or Treatment as Usual: Comparison of Response, Remission, and Suicidality https://pubmed.ncbi.nlm.nih.gov/28359... • • c-Fos and pERK, Which Is a Better Marker for Neuronal Activation and Central Sensitization After Noxious Stimulation and Tissue Injury? https://pubmed.ncbi.nlm.nih.gov/19898... • • Repetitive Transcranial Magnetic Stimulation in the Treatment of Bipolar Disorder https://pubmed.ncbi.nlm.nih.gov/33282... • • Efficacy of Active vs Sham Intermittent Theta Burst Transcranial Magnetic Stimulation for Patients With Bipolar Depression: A Randomized Clinical Trial https://pubmed.ncbi.nlm.nih.gov/33710... • • A Retrospective Analysis of Bipolar Depression Treated With Transcranial Magnetic Stimulation https://pubmed.ncbi.nlm.nih.gov/33169... • • When to Hold and When to Fold: Early Prediction of Nonresponse to Transcranial Magnetic Stimulation in Major Depressive Disorder https://pubmed.ncbi.nlm.nih.gov/38458... • • Dosing Transcranial Magnetic Stimulation in Major Depressive Disorder: Relations Between Number of Treatment Sessions and Effectiveness in a Large Patient Registry https://pubmed.ncbi.nlm.nih.gov/37827... • • Sequenced Treatment Alternatives to Relieve Depression (STAR*D): Rationale and Design https://pubmed.ncbi.nlm.nih.gov/15061... • • Single-Dose Synthetic Psilocybin With Psychotherapy for Treatment-Resistant Bipolar Type II Major Depressive Episodes: A Nonrandomized Controlled Trial https://pubmed.ncbi.nlm.nih.gov/38055...

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